Annihilate (verb)

1. To reduce to nothing; destroy completely.
2. To defeat completely; crush.

Origin:

Late latin annihilatus, past participle of annihilari, from latin ad- + nihil nothing.

Examples:

1. The enemy's army was annihilated.
2. The new drug has the ability to annihilate cancer cells.
3. The company was able to annihilate its competition.
4. The storm annihilated the coastal town.
5. His reputation was annihilated by the scandal.