- Inclined to oppose or fight against someone or something.
- Having an opposing or conflicting action.
Early 17th century (in the sense "opposed to each other"): from greek antagonistikos, from antagonistēs "opponent" (see antagonist).
- The two companies had an antagonistic relationship, constantly trying to one-up each other.
- The young boy had an antagonistic attitude towards authority figures.
- The relationship between the two countries was antagonistic, with both sides unwilling to compromise.
- The new policy was met with antagonistic reactions from the employees.
- The drug had an antagonistic effect on the patient's existing medication.