Derange (verb)

1. To disturb the normal state or arrangement of something.
2. To throw into confusion or disorder.
3. To affect the mind and cause irrational or abnormal behavior.

Origin:

From old french desranger ("to disturb, disarrange"), from des- ("dis-") + ranger ("to arrang.e")

Examples:

1. The storm deranged the entire city, leaving streets flooded and power lines down.
2. The news of his death deranged her, she couldn't stop crying.
3. The explosion deranged the building's structure, causing it to collapse.
4. The drug deranged his mind, making him paranoid and delusional.
5. The hacker"s actions deranged the company"s computer systems, causing extensive damage.