Despise (verb)

1. Regard with disgust and hatred.
2. Refuse to do something as beneath one's dignity.

Origin:

Late middle english: from old french despirer, from latin despicere, from de- "down" + specere "look".

Examples:

1. I despise people who are cruel to animals.
2. He despises manual labor, he's always been a desk jockey.
3. She despises him for the way he treated her.
4. He despises being treated like a child.
5. He despises the way the government is run.