Despondent (adjective)

1. Feeling or showing deep despair.
2. Feeling or showing discouragement, hopelessness, or lack of spirit.

Origin:

From latin despondentem, present participle of despondere ("to give up, abandon"), from de- ("away") + spondere ("to promis.e")

Examples:

1. The despondent man sat alone on the park bench.
2. She was despondent after the break-up of her long-term relationship.
3. The team's defeat left the coach despondent.
4. He was despondent and had lost the will to live.
5. The patient was despondent after receiving the news of their terminal illness.