Estrange (verb)

1. Cause (someone) to be no longer close to or affectionate towards someone.
2. Remove (someone) from a familiar or usual environment.

Origin:

Late middle english: from old french estranger, from latin extraneare "make strange", from extraneus "stranger".

Examples:

1. His behavior had estranged him from his family.
2. She felt estranged from her own culture after living abroad for so long.
3. The war had estranged the two neighboring countries.
4. His actions have estranged him from his friends.
5. The decision to move away estranged them from their community.