Extermination (noun)

1. The action or process of killing all the members of a particular racial or ethnic group or political body.
2. The complete destruction of a species or population.

Origin:

Late 16th century: from latin exterminatio(n-), from exterminare "drive out, root out" (see exterminate).

Examples:

1. The extermination of the Jews during the Holocaust is one of the darkest moments in human history.
2. The extermination of the native peoples of the Americas was a tragedy that has had lasting effects.
3. The extermination of the species was caused by the destruction of their natural habitat.
4. The extermination of the pests was necessary to protect the crops.
5. The extermination of the virus required a coordinated effort by scientists and healthcare workers.