Extirpation (noun)

1. The complete elimination or removal of something.
2. The act of destroying or wiping out a species, population or cultural group.
3. The eradication or extermination of a disease, pest, or harmful organism.

Origin:

Derived from the latin word 'extirpare' meaning to uproot, destroy or eliminate.

Examples:

1. The extirpation of invasive plant species was critical for restoring native ecosystems.
2. The extirpation of the disease was a major medical breakthrough.
3. The extirpation of wildlife for commercial purposes threatened the balance of ecosystems.
4. The extirpation of cultural traditions and practices was a tragic loss for future generations.
5. The extirpation of small business in the area was a concern for local economic stability.