Frazzle (verb)

1. To wear out or exhaust someone or something.
2. To exhaust or wear out someone or something, especially by overuse or prolonged stress.

Origin:

From frazzled (adjective) which is of uncertain origin, it means to wear out or exhaust someone or something.

Examples:

1. The long hike frazzled her.
2. The intense heat frazzled the plants.
3. The constant noise frazzled the dog.
4. The stress of the job frazzled him.
5. The constant demands frazzled her nerves.