Incapacitate (verb)

1. To render someone unable to do something.
2. To disable or make someone unable to perform certain functions.

Origin:

From in- + capable, from latin incapax "incapable".

Examples:

1. The injury incapacitated him and he was unable to walk.
2. The disease incapacitated her and she was unable to work.
3. The drug incapacitated the kidnapper and police was able to rescue the hostages.
4. The accident incapacitated the pilot and the plane was forced to make an emergency landing.
5. The stroke incapacitated him and he was unable to speak.