Infarction (noun)

1. The death of tissue in an organ or body part due to a blocked blood supply, usually due to a blood clot.
2. A localized area of necrosis resulting from obstruction of the blood supply.

Origin:

Mid 19th century: from latin infarctus, from in- 'into' + flectere 'to bend' (with reference to a blocked blood vessel).

Examples:

1. The heart attack was caused by an infarction in one of the coronary arteries.
2. The infarction in the brain resulted in a stroke.
3. The infarction in the leg led to the amputation of the limb.
4. The infarction was diagnosed using an X-ray and a CT scan.
5. The infarction was treated with a combination of medication and surgery.