Irreparable (adjective)

1. Unfixable, incurable, or beyond repair.
2. Permanent, irredeemable, or incapable of being corrected.

Origin:

Derived from the latin word 'irreparabilis' meaning unable to be repaired or fixed.

Examples:

1. The irreparable damage to the ecosystem was caused by decades of pollution and neglect.
2. The irreparable harm to the reputation of the company was caused by the scandal.
3. The irreparable loss of the priceless artwork was a tragedy for the art world.
4. The irreparable mistake in the calculation had serious consequences for the project.
5. The irreparable breach of trust between the partners was the main reason for the breakup.