Irreverence (noun)

1. A lack of respect for a person or thing that is usually respected.
2. A lack of reverence or a disrespectful attitude towards something considered sacred or holy.

Origin:

From the latin "irreverentia" which is composed of the prefix "in-" meaning "not" and the noun "reverentia" meaning "reverence".

Examples:

1. The young man's irreverence towards his elders was considered disrespectful.
2. The comedian's irreverence towards religion caused a lot of controversy.
3. The artist's irreverence towards traditional art forms was considered avant-garde.
4. The scientist's irreverence towards the status quo led to many groundbreaking discoveries.
5. The author's irreverence towards authority was reflected in their literature.