Loser (noun)

1. A person or thing that loses in a competition or contest.
2. A person who is not successful in their personal or professional life.
3. A person who is considered to be at a disadvantage in a particular situation.

Origin:

Mid 19th century: of unknown origin.

Examples:

1. The team was filled with losers.
2. The company was run by losers.
3. He was a constant loser in love.
4. He is a big loser in the stock market.
5. She is a loser for not taking the opportunity.