Madden (verb)

1. Make (someone) extremely angry.
2. Drive (someone) insane.
3. Frustrate or annoy (someone) greatly.

Origin:

Middle english: from old english gemyndgian "make mad".

Examples:

1. The constant noise maddened her.
2. His behavior maddened her.
3. The delay maddened the passengers.
4. The injustice maddened the crowd.
5. The constant interruptions maddened the speaker.