Malady (noun)

1. A disease or disorder of the body or mind.
2. An ailment or complaint.

Origin:

Middle english: from old french maladie, from malade "sick", from medieval latin maladia, from malus "bad".

Examples:

1. The doctor diagnosed the malady as a rare form of cancer.
2. He had been suffering from a mysterious malady for months.
3. The malady spread rapidly through the population.
4. The malady was caused by a deficiency of vitamin C.
5. She was finally cured of her long-standing malady.