Malignancy (noun)

1. The state or condition of being malignant; the quality or condition of being malignant.
2. A malignant tumor or growth.

Origin:

From the latin word "malignus" meaning "wicked" or "evil" and "ancy" meaning "condition" or "state". the word first appeared in english in the mid-16th century.

Examples:

1. The doctor said that the malignancy in her breast had spread to her lymph nodes.
2. The malignancy was so aggressive that it had already metastasized to other parts of her body.
3. The patient was told that the malignancy was inoperable and that she had only months to live.
4. The malignancy was so advanced that it had already infiltrated into surrounding tissue.
5. Despite aggressive treatment, the malignancy continued to spread, and the patient eventually passed away.