Perforation (noun)

1. A small hole or series of holes made in something.
2. The act of making a hole or series of holes in something.
3. A break or weakness in a surface, material, or membrane.

Origin:

From latin perforare, meaning 'to pierce'.

Examples:

1. The perforations in the paper made it easy to tear along the dotted line.
2. The perforation of the tire was caused by a sharp object on the road.
3. The perforation of the eardrum was a common side effect of the treatment.
4. The perforation of the steel plate was accomplished using a high-powered laser.
5. The perforation of the ozone layer was a major concern for the planet's health.