Psychopathy (noun)

1. A personality disorder characterized by persistent antisocial behavior, impaired empathy and remorse, and bold, disinhibited, and egotistical traits.
2. A psychological condition characterized by a persistent pattern of manipulation and disregard for the rights of others.

Origin:

From greek ψυχή (psychē, "mind, soul") + -πάθεια (-patheia, "suffering, disease").

Examples:

1. The criminal was diagnosed as a psychopath.
2. The psychopath had a complete lack of empathy for his victims.
3. His behavior suggested that he might be a psychopath.
4. The psychopath's charm and manipulativeness made it difficult for people to see through him.
5. The psychopath's actions were driven by a need for power and control.