Significance (noun)

1. The importance or relevance of something.
2. The meaning or effect of something.
3. The quality of being worthy of notice or attention.
4. A meaning that is implied or suggested, rather than plainly stated.

Origin:

Late 16th century: from late latin significantia, from significare "indicate".

Examples:

1. The significance of the discovery was not fully understood at the time.
2. The significance of his resignation was immediately apparent.
3. The findings have great significance for future research.
4. The significance of the symbols in the painting is still debated.
5. The significance of the election results was not lost on anyone.