Smallpox (noun)

An infectious and often fatal disease caused by the variola virus, characterized by fever and a rash of pustules on the skin.

Origin:

Late middle english: from old english smæl "small" + pox "pustule", translating latin variola.

Examples:

1. Despite a successful global vaccination campaign, smallpox killed an estimated 300–500 million people in the 20th century.
2. The World Health Organization (WHO) certified the eradication of smallpox in 1979.
3. Symptoms of smallpox include high fever, fatigue, and headache, followed by the development of a rash.
4. Smallpox vaccine, the first successful vaccine to be developed, was introduced by Edward Jenner in 1796.
5. The last known natural case of smallpox occurred in Somalia in 1977.