Transsexualism (noun)

1. A condition in which a person identifies with a gender that is different from the one they were assigned at birth.
2. A person who identifies with a gender that is different from the one they were assigned at birth.

Origin:

Derived from the prefix "trans-" meaning "across" or "beyond" and "sexual" meaning "relating to sexual orientation or gender identity".

Examples:

1. Transsexualism is a complex and often challenging issue, both for the individuals who experience it and for society as a whole.
2. Many people who struggle with transsexualism feel a deep sense of discomfort with the gender they were assigned at birth.
3. Transsexualism has been recognized as a medical condition for several decades, and many medical and psychological professionals offer support and treatment for individuals who experience it.
4. Some people with transsexualism choose to undergo hormone therapy and/or surgery in order to align their physical appearance with their gender identity.
5. The experience of transsexualism can vary greatly from person to person, but most individuals who experience it feel a strong sense of validation and liberation when they are finally able to express their true gender identity.