Unease (noun)

1. A feeling of discomfort, anxiety or worry; lack of ease.
2. A state of being not comfortable or at ease.

Origin:

Un + ease.

Examples:

1. The employee's sudden absence caused unease among the staff.
2. She could sense the unease in his voice when he asked her about her day.
3. The news of the merger caused unease among the shareholders.
4. He had an unease feeling that something was not right.
5. The uneasy silence in the room indicated that there was an underlying problem.