Unresponsive (adjective)

1. Not reacting or responding to something; indifferent.
2. Not able to be controlled or influenced.

Origin:

Mid 17th century: from un- (expressing negation) + responsive.

Examples:

1. The patient was unresponsive.
2. An unresponsive audience.
3. Unresponsive to treatment.
4. Unresponsive to commands.
5. The market was unresponsive.