Difference (noun)

1. The state or quality of being different; unlikeness; distinction; change.
2. A point or respect in which things differ; a variation or discrepancy.

Origin:

From middle english differaunce, from old french difference, from latin differentia, from different- ("different") + -ia (suffix forming nouns of quality or condition).

Examples:

1. There's a significant difference in the prices of these two cars.
2. The difference between these two paintings is the use of color.
3. The teacher noticed a difference in the student's behavior.
4. The company's profits showed a major difference after implementing the new strategy.
5. The difference in the climate of these two regions is quite marked.