Gangrene (noun)

1. The death of body tissue, typically as a result of a lack of blood supply.
2. The death of body tissue due to a lack of blood supply, often resulting in the affected body part turning black and eventually dying and falling off.

Origin:

Late 16th century: from french gangrène, from greek gangraina, from gangras "ulcer".

Examples:

1. The patient had developed gangrene in his foot.
2. Gangrene can be caused by an injury or infection.
3. Gangrene can occur in any part of the body, but it is more common in the extremities.
4. The amputation of the limb was necessary due to the gangrene.
5. Gangrene is a serious medical condition that can lead to death if not treated promptly.