Malediction (noun)

1. A curse or an expression of evil wishes against someone or something.
2. The act of speaking ill of someone or something; the act of cursing.

Origin:

From the latin word "maledictio" meaning "curse" or "malicious speech".

Examples:

1. She spat out a malediction at her enemy.
2. He muttered a malediction under his breath.
3. The malediction was a powerful spell that was meant to cause harm.
4. The witch's malediction was feared by all who heard it.
5. Malediction is a form of verbal abuse.