Screwup (noun)

1. A mistake or blunder, especially a significant one.
2. A failure to function properly or as expected.

Origin:

Originated from the phrase "to screw up" which means to make a mistake or to do something wrong.

Examples:

1. The screwup in the manufacturing process led to a recall of the product.
2. It was a real screwup when the company didn't deliver the goods on time.
3. She made a major screwup when she accidentally deleted the entire document.
4. It was a screwup that the concert was cancelled.
5. The screwup caused a lot of inconvenience for the customers.