Unsettle (verb)

1. Make (someone) feel worried, nervous, or uneasy.
2. Disrupt or upset the balance or stability of.

Origin:

Early 17th century: from un-1 (expressing negation) + settle.

Examples:

1. The sudden announcement unsettled the employees.
2. The news of the recession unsettled the stock market.
3. His behavior unsettled her and made her feel uncomfortable.
4. The storm unsettled the ship and caused it to sway.
5. The change in plans unsettled their routine and caused stress.